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Codon-by-Codon Modulation of Translational Speed and Accuracy Via mRNA Folding
Rapid cell growth demands fast protein translational elongation to alleviate ribosome shortage. However, speedy elongation undermines translational accuracy because of a mechanistic tradeoff. Here we provide genomic evidence in budding yeast and mouse embryonic stem cells that the efficiency–accurac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106722/ https://ncbi.nlm.nih.gov/pubmed/25051069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001910 |
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