ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis

Alternative reading frame (ARF) is a tumor suppressor protein that senses oncogenic and other stressogenic signals. It can trigger p53-dependent and -independent responses with cell cycle arrest and apoptosis induction being the most prominent ones. Other ARF activities, particularly p53-independent...

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Библиографические подробности
Главные авторы: Kotsinas, Athanassios, Papanagnou, Panagiota, Evangelou, Konstantinos, Trigas, George C., Kostourou, Vassiliki, Townsend, Paul, Gorgoulis, Vassilis G.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2014
Предметы:
Genetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106421/
https://ncbi.nlm.nih.gov/pubmed/25101116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00236
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