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Non-Canonical Functions of the ARF Tumor Suppressor in Development and Tumorigenesis

P14ARF (ARF; Alternative Reading Frame) is an extensively characterized tumor suppressor which, in response to oncogenic stimuli, mediates cell cycle arrest and apoptosis via p53-dependent and independent routes. ARF has been shown to be frequently lost through CpG island promoter methylation in a w...

詳細記述

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書誌詳細
出版年:Biomolecules
主要な著者: Lagopati, Nefeli, Belogiannis, Konstantinos, Angelopoulou, Andriani, Papaspyropoulos, Angelos, Gorgoulis, Vassilis
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827855/
https://ncbi.nlm.nih.gov/pubmed/33445626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11010086
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