The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

Oncogenic stimuli trigger the DNA damage response (DDR) and induction of the alternative reading frame (ARF) tumor suppressor, both of which can activate the p53 pathway and provide intrinsic barriers to tumor progression. However, the respective timeframes and signal thresholds for ARF induction an...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Evangelou, K, Bartkova, J, Kotsinas, A, Pateras, I S, Liontos, M, Velimezi, G, Kosar, M, Liloglou, T, Trougakos, I P, Dyrskjot, L, Andersen, C L, Papaioannou, M, Drosos, Y, Papafotiou, G, Hodny, Z, Sosa-Pineda, B, Wu, X-R, Klinakis, A, Ørntoft, T, Lukas, J, Bartek, J, Gorgoulis, V G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792440/
https://ncbi.nlm.nih.gov/pubmed/23852374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.76
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars