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Effects of Potent Inhibitors of the Retinoid Cycle on Visual Function and Photoreceptor Protection from Light Damage in Mice()

Regeneration of the chromophore 11-cis-retinal is essential for the generation of light-sensitive visual pigments in the vertebrate retina. A deficiency in 11-cis-retinal production leads to congenital blindness in humans; however, a buildup of the photoisomerized chromophore can also be detrimental...

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Detalhes bibliográficos
Main Authors: Maeda, Akiko, Maeda, Tadao, Golczak, Marcin, Imanishi, Yoshikazu, Leahy, Patrick, Kubota, Ryo, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106413/
https://ncbi.nlm.nih.gov/pubmed/16837623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.106.026823
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