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Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle
In vertebrate retinal photoreceptors, photoisomerization of opsin-bound visual chromophore 11-cis-retinal to all-trans-retinal triggers phototransduction events. Regeneration of the chromophore is a critical step in restoring photoreceptors to their dark-adapted state. This regeneration process, cal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1149451/ https://ncbi.nlm.nih.gov/pubmed/15917330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503318102 |
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