Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface

Cobra cardiotoxins (CTX) are a family of three-fingered basic polypeptides known to interact with diverse targets such as heparan sulfates, sulfatides, and integrins on cell surfaces. After CTX bind to the membrane surface, they are internalized to intracellular space and exert their cytotoxicity vi...

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מידע ביבליוגרפי
Main Authors: Lee, Shao-Chen, Lin, Chien-Chu, Wang, Chia-Hui, Wu, Po-Long, Huang, Hsuan-Wei, Chang, Chung-I, Wu, Wen-guey
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
Glycobiology and Extracellular Matrices
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106332/
https://ncbi.nlm.nih.gov/pubmed/24898246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557157
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