NHERF2/NHERF3 Protein Heterodimerization and Macrocomplex Formation Are Required for the Inhibition of NHE3 Activity by Carbachol

NHERF1, NHERF2, and NHERF3 belong to the NHERF (Na(+)/H(+) exchanger regulatory factor) family of PSD-95/Discs-large/ZO-1 (PDZ) scaffolding proteins. Individually, each NHERF protein has been shown to be involved in the regulation of multiple receptors or transporters including Na(+)/H(+) exchanger...

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Hlavní autoři: Yang, Jianbo, Singh, Varsha, Chen, Tian-E, Sarker, Rafiquel, Xiong, Lishou, Cha, Boyoung, Jin, Shi, Li, Xuhang, Tse, C. Ming, Zachos, Nicholas C., Donowitz, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106321/
https://ncbi.nlm.nih.gov/pubmed/24867958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562413
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