Elevated Calcium Acutely Regulates Dynamic Interactions of NHERF2 and NHE3 Proteins in Opossum Kidney (OK) Cell Microvilli

The brush border (BB) Na(+)/H(+) exchanger NHE3 is rapidly activated or inhibited by changes in trafficking, which mimics renal and intestinal physiology. However, there is a paradox in that NHE3 has limited mobility in the BB due to its binding to the multi-PDZ domain containing the NHERF family. T...

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Main Authors: Zhu, Xinjun, Cha, Boyoung, Zachos, Nicholas C., Sarker, Rafiquel, Chakraborty, Molee, Chen, Tian-e, Kovbasnjuk, Olga, Donowitz, Mark
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186394/
https://ncbi.nlm.nih.gov/pubmed/21799002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230219
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