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Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat

20-HETE (20-hydroxyeicosatetraenoic acid), a vasoconstrictor metabolite of arachidonic acid formed through the action of CYP4A (cytochrome P450-4A) in vascular smooth muscle cells, has been implicated in the development of hypertension and vascular dysfunction. There have been a number of reports in...

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Detalhes bibliográficos
Main Authors: LUKASZEWICZ, Kathleen M., LOMBARD, Julian H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106241/
https://ncbi.nlm.nih.gov/pubmed/23438293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20120483
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