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Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat
20-HETE (20-hydroxyeicosatetraenoic acid), a vasoconstrictor metabolite of arachidonic acid formed through the action of CYP4A (cytochrome P450-4A) in vascular smooth muscle cells, has been implicated in the development of hypertension and vascular dysfunction. There have been a number of reports in...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106241/ https://ncbi.nlm.nih.gov/pubmed/23438293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20120483 |
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