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Mechanism of impaired afferent arteriole myogenic response in Dahl salt-sensitive rats: role of 20-HETE

The afferent arteriole (Af-Art) controls glomerular capillary pressure, an important determinant of glomerular injury. Af-Art myogenic response is mediated by ATP, and ATP signaling is in turn mediated by 20-HETE. Dahl salt-sensitive rats (Dahl SS) have decreased renal 20-HETE production. We hypothe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Renal Physiol
Prif Awduron: Ren, YiLin, D'Ambrosio, Martin A., Garvin, Jeffrey L., Peterson, Edward L., Carretero, Oscar A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250233/
https://ncbi.nlm.nih.gov/pubmed/24990891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00283.2014
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