Atorvastatin Represses the Angiotensin 2-Induced Oxidative Stress and Inflammatory Response in Dendritic Cells via the PI3K/Akt/Nrf 2 Pathway

Dendritic cells (DCs), which are highly proficient antigen-presenting cells, play a complex role in both the initiation and progression of atherosclerosis. We tested the hypothesis that the anti-inflammatory and antioxidant effects of atorvastatin may be partly mediated by the phosphatidylinositol 3...

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Bibliographic Details
Main Authors: Ma, Yuanji, Chen, Zhaoyang, Zou, Yunzeng, Ge, Junbo
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106155/
https://ncbi.nlm.nih.gov/pubmed/25110549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/148798
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