Nrf2 Negatively Regulates Melanogenesis by Modulating PI3K/Akt Signaling

Nrf2 plays a role in protection of cells against oxidative stress and xenobiotic damage by regulating cytoprotective genes. In this study, we investigated the effect of Nrf2 on melanogenesis in normal human melanocytes (NHMCs). When NHMCs were transduced with a recombinant adenovirus expressing Nrf2...

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Detalles Bibliográficos
Autores principales: Shin, Jung-Min, Kim, Mi Yoon, Sohn, Kyung-Cheol, Jung, So-Young, Lee, Hae-Eul, Lim, Jae Woo, Kim, Sooil, Lee, Young-Ho, Im, Myung, Seo, Young-Joon, Kim, Chang Deok, Lee, Jeung-Hoon, Lee, Young, Yoon, Tae-Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999113/
https://ncbi.nlm.nih.gov/pubmed/24763530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096035
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