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The Mathematics of a Successful Deconvolution: A Quantitative Assessment of Mixture-Based Combinatorial Libraries Screened Against Two Formylpeptide Receptors

In the past 20 years, synthetic combinatorial methods have fundamentally advanced the ability to synthesize and screen large numbers of compounds for drug discovery and basic research. Mixture-based libraries and positional scanning deconvolution combine two approaches for the rapid identification o...

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Detalhes bibliográficos
Main Authors: Santos, Radleigh G., Appel, Jon R., Giulianotti, Marc A., Edwards, Bruce S., Sklar, Larry A., Houghten, Richard A., Pinilla, Clemencia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106117/
https://ncbi.nlm.nih.gov/pubmed/23722730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18066408
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