Selective Agonists and Antagonists of Formylpeptide Receptors: Duplex Flow Cytometry and Mixture-Based Positional Scanning Libraries

The formylpeptide receptor (FPR1) and formylpeptide-like 1 receptor (FPR2) are G protein–coupled receptors that are linked to acute inflammatory responses, malignant glioma stem cell metastasis, and chronic inflammation. Although several N-formyl peptides are known to bind to these receptors, more s...

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Autors principals: Pinilla, Clemencia, Edwards, Bruce S., Appel, Jon R., Yates-Gibbins, Tina, Giulianotti, Marc A., Medina-Franco, Jose L., Young, Susan M., Santos, Radleigh G., Sklar, Larry A., Houghten, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876812/
https://ncbi.nlm.nih.gov/pubmed/23788657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.086595
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