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DMRT1 protects male gonadal cells from retinoid-dependent sexual transdifferentiation
Mammalian sex determination initiates in the fetal gonad with specification of bipotential precursor cells into male Sertoli cells or female granulosa cells. This choice was long presumed to be irreversible, but genetic analysis in the mouse recently revealed that sexual fates must be maintained thr...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4105363/ https://ncbi.nlm.nih.gov/pubmed/24856513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.017 |
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