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DMRT1 prevents female reprogramming in the postnatal mammalian testis

Sex in mammals is determined in the foetal gonad by the presence or absence of the Y chromosome gene Sry, which controls whether bipotential precursor cells differentiate into testicular Sertoli cells or ovarian granulosa cells(1). This pivotal decision in a single gonadal cell type ultimately contr...

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Detalles Bibliográficos
Main Authors: Matson, Clinton K., Murphy, Mark W., Sarver, Aaron L., Griswold, Michael D., Bardwell, Vivian J., Zarkower, David
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150961/
https://ncbi.nlm.nih.gov/pubmed/21775990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10239
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