The mammalian Doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

[Image: see text] The switch from mitosis to meiosis is a unique feature of germ cell development. In mammals, meiotic initiation requires retinoic acid (RA), which activates meiotic inducers including Stra8, but how the switch to meiosis is controlled in male germ cells (spermatogonia) remains poor...

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Hlavní autoři: Matson, Clinton K., Murphy, Mark W., Griswold, Michael D., Yoshida, Shosei, Bardwell, Vivian J., Zarkower, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996490/
https://ncbi.nlm.nih.gov/pubmed/20951351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.09.010
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