Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway

BACKGROUND: Several lines of evidence have indicated that nitric oxide (NO) plays complex and diverse roles in modulation of pain/analgesia. However, the roles of charged and uncharged congeners of NO are less well understood. In the present study, the antinociceptive effect of the nitroxyl (HNO) do...

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Main Authors: Staurengo-Ferrari, Larissa, Zarpelon, Ana C., Longhi-Balbinot, Daniela T., Marchesi, Mario, Cunha, Thiago M., Alves-Filho, José C., Cunha, Fernando Q., Ferreira, Sergio H., Casagrande, Rubia, Miranda, Katrina M., Verri, Waldiceu A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104808/
https://ncbi.nlm.nih.gov/pubmed/24948073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharep.2014.04.003
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