The nitroxyl donor, Angeli’s salt, inhibits inflammatory hyperalgesia in rats

Nitric oxide modulates pain development. However, there is no evidence on the effect of nitroxyl (HNO/NO(−)) in nociception. Therefore, we addressed whether nitroxyl inhibits inflammatory hyperalgesia and its mechanism using the nitroxyl donor Angeli’s salt (AS; Na(2)N(2)O(3)). Mechanical hyperalges...

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Main Authors: Zarpelon, Ana C., Souza, Guilherme R., Cunha, Thiago M., Schivo, Ieda R.S., Marchesi, Mario, Casagrande, Rubia, Pinge-Filho, Phileno, Cunha, Fernando Q., Ferreira, Sergio H., Miranda, Katrina M., Verri, Waldiceu A.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666861/
https://ncbi.nlm.nih.gov/pubmed/23541720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.03.009
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