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Angeli’s Salt, a nitroxyl anion donor, reverses endothelin-1 mediated vascular dysfunction in murine aorta
Nitroglycerin (Gtn) is a treatment for cardiovascular patients due to its vasodilatory actions, but induces tolerance when given chronically. A proposed mechanism is the superoxide (O(2)(−))oxidative stress hypothesis, which suggests that Gtn increases O(2)(−) production. Nitric oxide (NO) exists in...
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| Publicado no: | Eur J Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777347/ https://ncbi.nlm.nih.gov/pubmed/28830679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2017.08.024 |
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