Synthesis, Biological, and Biophysical Studies of DAG-indololactones Designed as Selective Activators of RasGRP

The development of selective agents capable of discriminating between protein kinase C (PKC) isoforms and other diacylglycerol (DAG)-responsive C1 domain-containing proteins represents an important challenge. Recent studies have highlighted the role that Ras guanine nucleotide-releasing protein (Ras...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Garcia, Lia C., Donadío, Lucia Gandolfi, Mann, Ella, Kolusheva, Sofiya, Kedei, Noemi, Lewin, Nancy E., Hill, Colin S., Kelsey, Jessica S., Yang, Jing, Esch, Timothy E., Santos, Marina, Peach, Megan L., Kelley, James A., Blumberg, Peter M., Jelinek, Raz, Marquez, Victor E., Comin, Maria J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104769/
https://ncbi.nlm.nih.gov/pubmed/24794745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.04.024
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