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Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes
Waves of cyclin synthesis and degradation regulate the activity of Cdc2 protein kinase during the cell cycle. Cdc2 inactivation by Wee1B-mediated phosphorylation is necessary for arrest of the oocyte at G2-prophase, but it is unclear whether this regulation functions later during the metaphase to an...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104668/ https://ncbi.nlm.nih.gov/pubmed/21454751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1199211 |
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