Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes

The quality of mammalian oocytes declines with age, which negatively affects fertilization and developmental potential. The aging process often accompanies damages to macromolecules such as proteins, DNA, and lipids. To investigate if aged oocytes display an altered lipidome compared to young oocyte...

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Udgivet i:PLoS One
Main Authors: Mok, Hyuck Jun, Shin, Hyejin, Lee, Jae Won, Lee, Geun-Kyung, Suh, Chang Suk, Kim, Kwang Pyo, Lim, Hyunjung Jade
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755615/
https://ncbi.nlm.nih.gov/pubmed/26881843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148577
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