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Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes

The quality of mammalian oocytes declines with age, which negatively affects fertilization and developmental potential. The aging process often accompanies damages to macromolecules such as proteins, DNA, and lipids. To investigate if aged oocytes display an altered lipidome compared to young oocyte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Mok, Hyuck Jun, Shin, Hyejin, Lee, Jae Won, Lee, Geun-Kyung, Suh, Chang Suk, Kim, Kwang Pyo, Lim, Hyunjung Jade
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755615/
https://ncbi.nlm.nih.gov/pubmed/26881843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148577
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