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Cdc25A activity is required for the metaphase II arrest in mouse oocytes

Mammalian oocytes are arrested in metaphase of second meiosis (MII) until fertilization. This arrest is enforced by the cytostatic factor (CSF), which maintains the M-phase promoting factor (MPF) in a highly active state. Although the continuous synthesis and degradation of cyclin B to maintain the...

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Библиографические подробности
Главные авторы: Oh, Jeong Su, Susor, Andrej, Schindler, Karen, Schultz, Richard M., Conti, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635459/
https://ncbi.nlm.nih.gov/pubmed/23345398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.115592
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