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A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

Chaperones are abundant cellular proteins that promote the folding and function of their substrate proteins (clients). In vivo, chaperones also associate with a large and diverse set of co-factors (co-chaperones) that regulate their specificity and function. However, how these co-chaperones regulate...

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Библиографические подробности
Главные авторы: Taipale, Mikko, Tucker, George, Peng, Jian, Krykbaeva, Irina, Lin, Zhen-Yuan, Larsen, Brett, Choi, Hyungwon, Berger, Bonnie, Gingras, Anne-Claude, Lindquist, Susan
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104544/
https://ncbi.nlm.nih.gov/pubmed/25036637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.039
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