Analysis of protein complexes through model-based biclustering of label-free quantitative AP-MS data

Affinity purification followed by mass spectrometry (AP-MS) has become a common approach for identifying protein–protein interactions (PPIs) and complexes. However, data analysis and visualization often rely on generic approaches that do not take advantage of the quantitative nature of AP-MS. We pre...

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Main Authors: Choi, Hyungwon, Kim, Sinae, Gingras, Anne-Claude, Nesvizhskii, Alexey I
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913403/
https://ncbi.nlm.nih.gov/pubmed/20571534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.41
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