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Significance Analysis of Spectral Count Data in Label-free Shotgun Proteomics

Spectral counting has become a commonly used approach for measuring protein abundance in label-free shotgun proteomics. At the same time, the development of data analysis methods has lagged behind. Currently most studies utilizing spectral counts rely on simple data transforms and posthoc correction...

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Detalhes bibliográficos
Main Authors: Choi, Hyungwon, Fermin, Damian, Nesvizhskii, Alexey I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596341/
https://ncbi.nlm.nih.gov/pubmed/18644780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800203-MCP200
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