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Abacus: A computational tool for extracting and pre-processing spectral count data for label-free quantitative proteomic analysis

We describe Abacus, a computational tool for extracting spectral counts from tandem mass spectrometry based proteomic datasets. The program aggregates data from multiple experiments, adjusts spectral counts to accurately account for peptides shared across multiple proteins, and performs common norma...

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Detalhes bibliográficos
Main Authors: Fermin, Damian, Basrur, Venkatesha, Yocum, Anastasia K., Nesvizhskii, Alexey I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113614/
https://ncbi.nlm.nih.gov/pubmed/21360675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000650
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