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Adaptive Discriminant Function Analysis and Re-ranking of MS/MS Database Search Results for Improved Peptide Identification in Shotgun Proteomics

Robust statistical validation of peptide identifications obtained by tandem mass spectrometry and sequence database searching is an important task in shotgun proteomics. PeptideProphet is a commonly used computational tool that computes confidence measures for peptide identifications. In this paper,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ding, Ying, Choi, Hyungwon, Nesvizhskii, Alexey I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744223/
https://ncbi.nlm.nih.gov/pubmed/18788775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr800484x
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