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Adaptive Discriminant Function Analysis and Re-ranking of MS/MS Database Search Results for Improved Peptide Identification in Shotgun Proteomics

Robust statistical validation of peptide identifications obtained by tandem mass spectrometry and sequence database searching is an important task in shotgun proteomics. PeptideProphet is a commonly used computational tool that computes confidence measures for peptide identifications. In this paper,...

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Main Authors: Ding, Ying, Choi, Hyungwon, Nesvizhskii, Alexey I.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744223/
https://ncbi.nlm.nih.gov/pubmed/18788775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr800484x
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