Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial

AIMS: The risk of stroke in patients with atrial fibrillation (AF) increases with age. In the ARISTOTLE trial, apixaban when compared with warfarin reduced the rate of stroke, death, and bleeding. We evaluated these outcomes in relation to patient age. METHODS AND RESULTS: A total of 18 201 patients...

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Detalhes bibliográficos
Main Authors: Halvorsen, Sigrun, Atar, Dan, Yang, Hongqiu, De Caterina, Raffaele, Erol, Cetin, Garcia, David, Granger, Christopher B., Hanna, Michael, Held, Claes, Husted, Steen, Hylek, Elaine M., Jansky, Petr, Lopes, Renato D., Ruzyllo, Witold, Thomas, Laine, Wallentin, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104493/
https://ncbi.nlm.nih.gov/pubmed/24561548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu046
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