Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial

AIMS: The risk of stroke in patients with atrial fibrillation (AF) increases with age. In the ARISTOTLE trial, apixaban when compared with warfarin reduced the rate of stroke, death, and bleeding. We evaluated these outcomes in relation to patient age. METHODS AND RESULTS: A total of 18 201 patients...

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Autors principals: Halvorsen, Sigrun, Atar, Dan, Yang, Hongqiu, De Caterina, Raffaele, Erol, Cetin, Garcia, David, Granger, Christopher B., Hanna, Michael, Held, Claes, Husted, Steen, Hylek, Elaine M., Jansky, Petr, Lopes, Renato D., Ruzyllo, Witold, Thomas, Laine, Wallentin, Lars
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104493/
https://ncbi.nlm.nih.gov/pubmed/24561548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu046
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