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Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial

AIMS: The risk of stroke in patients with atrial fibrillation (AF) increases with age. In the ARISTOTLE trial, apixaban when compared with warfarin reduced the rate of stroke, death, and bleeding. We evaluated these outcomes in relation to patient age. METHODS AND RESULTS: A total of 18 201 patients...

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Bibliografiska uppgifter
Huvudupphovsmän: Halvorsen, Sigrun, Atar, Dan, Yang, Hongqiu, De Caterina, Raffaele, Erol, Cetin, Garcia, David, Granger, Christopher B., Hanna, Michael, Held, Claes, Husted, Steen, Hylek, Elaine M., Jansky, Petr, Lopes, Renato D., Ruzyllo, Witold, Thomas, Laine, Wallentin, Lars
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104493/
https://ncbi.nlm.nih.gov/pubmed/24561548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu046
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