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Quantitative flux analysis reveals folate-dependent NADPH production

ATP is the dominant energy source in animals for mechanical and electrical work (e.g., muscle contraction, neuronal firing). For chemical work, there is an equally important role for NADPH, which powers redox defense and reductive biosynthesis(1). The most direct route to produce NADPH from glucose...

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Hlavní autoři: Fan, Jing, Ye, Jiangbin, Kamphorst, Jurre J., Shlomi, Tomer, Thompson, Craig B., Rabinowitz, Joshua D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104482/
https://ncbi.nlm.nih.gov/pubmed/24805240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13236
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