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Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

The function of many eukaryotic proteins is regulated by highly dynamic changes in their nucleocytoplasmic distribution. The ability to precisely and reversibly control nuclear translocation would, therefore, allow dissecting and engineering cellular networks. Here we develop a genetically encoded,...

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Bibliografski detalji
Glavni autori: Niopek, Dominik, Benzinger, Dirk, Roensch, Julia, Draebing, Thomas, Wehler, Pierre, Eils, Roland, Di Ventura, Barbara
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104460/
https://ncbi.nlm.nih.gov/pubmed/25019686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5404
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