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Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

The function of many eukaryotic proteins is regulated by highly dynamic changes in their nucleocytoplasmic distribution. The ability to precisely and reversibly control nuclear translocation would, therefore, allow dissecting and engineering cellular networks. Here we develop a genetically encoded,...

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Bibliografische gegevens
Hoofdauteurs: Niopek, Dominik, Benzinger, Dirk, Roensch, Julia, Draebing, Thomas, Wehler, Pierre, Eils, Roland, Di Ventura, Barbara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104460/
https://ncbi.nlm.nih.gov/pubmed/25019686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5404
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