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Impact of residues remote from the catalytic centre on enzyme catalysis of copper nitrite reductase

Enzyme mechanisms are often probed by structure-informed point mutations and measurement of their effects on enzymatic properties to test mechanistic hypotheses. In many cases, the challenge is to report on complex, often inter-linked elements of catalysis. Evidence for long-range effects on enzyme...

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Detalhes bibliográficos
Principais autores: Leferink, Nicole G. H., Antonyuk, Svetlana V., Houwman, Joseline A., Scrutton, Nigel S., Eady, Robert R., Hasnain, S. Samar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104443/
https://ncbi.nlm.nih.gov/pubmed/25022223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5395
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