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Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague–Dawley rats and C57BL/6 mice

Although the structure and function of the AhR are conserved, emerging evidence suggests that downstream effects are species-specific. In this study, rat hepatic gene expression data from the DrugMatrix database (National Toxicology Program) were compared to mouse hepatic whole-genome gene expressio...

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Autori principali: Nault, Rance, Kim, Suntae, Zacharewski, Timothy R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104405/
https://ncbi.nlm.nih.gov/pubmed/23238561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.11.028
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