Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells

Cell populations can be strikingly heterogeneous, composed of multiple cellular states, each exhibiting stochastic noise in its gene expression. A major challenge is to disentangle these two types of variability and to understand the dynamic processes and mechanisms that control them. Embryonic stem...

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Autores principales: Singer, Zakary S., Yong, John, Tischler, Julia, Hackett, Jamie A., Altinok, Alphan, Surani, M. Azim, Cai, Long, Elowitz, Michael B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104113/
https://ncbi.nlm.nih.gov/pubmed/25038413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.029
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