Mechanical Properties of Base-Modified DNA Are Not Strictly Determined by Base Stacking or Electrostatic Interactions

This work probes the mystery of what balance of forces creates the extraordinary mechanical stiffness of DNA to bending and twisting. Here we explore the relationship between base stacking, functional group occupancy of the DNA minor and major grooves, and DNA mechanical properties. We study double-...

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Autors principals: Peters, Justin P., Mogil, Lauren S., McCauley, Micah J., Williams, Mark C., Maher, L. James
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Proteins and Nucleic Acids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104048/
https://ncbi.nlm.nih.gov/pubmed/25028886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.066
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