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Dual Binding Modes for an HMG Domain from Human HMGB2 on DNA

High mobility group B (HMGB) proteins contain two HMG box domains known to bind without sequence specificity into the DNA minor groove, slightly intercalating between basepairs and producing a strong bend in the DNA backbone. We use optical tweezers to measure the forces required to stretch single D...

詳細記述

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書誌詳細
主要な著者: McCauley, Micah, Hardwidge, Philip R., Maher, L. James, Williams, Mark C.
フォーマット: Artigo
言語:Inglês
出版事項: Biophysical Society 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366535/
https://ncbi.nlm.nih.gov/pubmed/15833996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052068
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