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Dual Binding Modes for an HMG Domain from Human HMGB2 on DNA
High mobility group B (HMGB) proteins contain two HMG box domains known to bind without sequence specificity into the DNA minor groove, slightly intercalating between basepairs and producing a strong bend in the DNA backbone. We use optical tweezers to measure the forces required to stretch single D...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366535/ https://ncbi.nlm.nih.gov/pubmed/15833996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052068 |
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