Mechanical Properties of Base-Modified DNA Are Not Strictly Determined by Base Stacking or Electrostatic Interactions

This work probes the mystery of what balance of forces creates the extraordinary mechanical stiffness of DNA to bending and twisting. Here we explore the relationship between base stacking, functional group occupancy of the DNA minor and major grooves, and DNA mechanical properties. We study double-...

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Detalhes bibliográficos
Main Authors: Peters, Justin P., Mogil, Lauren S., McCauley, Micah J., Williams, Mark C., Maher, L. James
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104048/
https://ncbi.nlm.nih.gov/pubmed/25028886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.066
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