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Optical Tweezers Experiments Resolve Distinct Modes of DNA-Protein Binding

Optical tweezers are ideally suited to perform force microscopy experiments that isolate a single biomolecule, which then provides multiple binding sites for ligands. The captured complex may be subjected to a spectrum of forces, inhibiting or facilitating ligand activity. In the following experimen...

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Detalhes bibliográficos
Main Authors: McCauley, Micah J., Williams, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753391/
https://ncbi.nlm.nih.gov/pubmed/19173290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21123
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