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Rapid Estrogen Signaling Negatively Regulates PTEN Activity Through Phosphorylation in Endometrial Cancer Cells

Hyperestrogenicity is a risk factor for endometrial cancer. 17β-estradiol (E2) is known to stimulate both genomic and nongenomic estrogen receptor-α (ERα) actions in a number of reproductive tissues. However, the contributions of transcription-independent ERα signaling on normal and malignant endome...

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Detalhes bibliográficos
Main Authors: Scully, Melanie M., Palacios-Helgeson, Leslie K., Wah, Lah S., Jackson, Twila A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103875/
https://ncbi.nlm.nih.gov/pubmed/24844349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0184-z
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