Estrogen affects the negative feedback loop of PTENP1-miR200c to inhibit PTEN expression in the development of endometrioid endometrial carcinoma

Endometrial carcinoma is one of the most common malignancies in the female reproductive system. It is well-known that estrogen plays an important role in the pathogenesis of endometrioid endometrial carcinoma (EEC), and induces the cancer suppressor gene PTEN deletion. However, how estrogen affects...

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Udgivet i:Cell Death Dis
Main Authors: Chen, Ruichao, Zhang, Minfen, Liu, Wenya, Chen, Hui, Cai, Tonghui, Xiong, Hanzhen, Sheng, Xiujie, Liu, Shaoyan, Peng, Juan, Wang, Fang, Chen, Hao, Lin, Wanrun, Xu, Xuehu, Zheng, Wenxin, Jiang, Qingping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315040/
https://ncbi.nlm.nih.gov/pubmed/30584245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1207-4
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