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C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis
Homeobox A9 (HOXA9) is a homeodomain-containing transcription factor that plays a key role in hematopoietic stem cell expansion and is commonly deregulated in human acute leukemias. A variety of upstream genetic alterations in acute myeloid leukemia (AML) lead to overexpression of HOXA9, almost alwa...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
National Academy of Sciences
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103350/ https://ncbi.nlm.nih.gov/pubmed/24958854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402238111 |
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