Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes

Clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems protect bacteria and archaea from infection by viruses and plasmids. Central to this defense is a ribonucleoprotein complex that produces RNA-guided cleavage of foreign nucleic acids. In DNA-targetin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Szczelkun, Mark D., Tikhomirova, Maria S., Sinkunas, Tomas, Gasiunas, Giedrius, Karvelis, Tautvydas, Pschera, Patrizia, Siksnys, Virginijus, Seidel, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103346/
https://ncbi.nlm.nih.gov/pubmed/24912165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402597111
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker