NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery

Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and consequently inhibits global cellular protein synthesi...

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Detalhes bibliográficos
Main Authors: Barry, Gerald, Varela, Mariana, Ratinier, Maxime, Blomström, Anne-Lie, Caporale, Marco, Seehusen, Frauke, Hahn, Kerstin, Schnettler, Esther, Baumgärtner, Wolfgang, Kohl, Alain, Palmarini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2014
Assuntos:
Animal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103064/
https://ncbi.nlm.nih.gov/pubmed/24828331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.065425-0
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