NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery

Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and consequently inhibits global cellular protein synthesi...

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Bibliografske podrobnosti
Main Authors: Barry, Gerald, Varela, Mariana, Ratinier, Maxime, Blomström, Anne-Lie, Caporale, Marco, Seehusen, Frauke, Hahn, Kerstin, Schnettler, Esther, Baumgärtner, Wolfgang, Kohl, Alain, Palmarini, Massimo
Format: Artigo
Jezik:Inglês
Izdano: Society for General Microbiology 2014
Teme:
Animal
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103064/
https://ncbi.nlm.nih.gov/pubmed/24828331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.065425-0
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