The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma

DNA methyltransferase inhibitors (DNMTi) and histone deacetylase inhibitors (HDACi) are under investigation for the treatment of cancer, including the plasma cell malignancy multiple myeloma (MM). Evidence exists that DNA damage and repair contribute to the cytotoxicity mediated by the DNMTi decitab...

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Autores principales: Maes, Ken, Smedt, Eva De, Lemaire, Miguel, Raeve, Hendrik De, Menu, Eline, Van Valckenborgh, Els, McClue, Steve, Vanderkerken, Karin, De Bruyne, Elke
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102796/
https://ncbi.nlm.nih.gov/pubmed/24833108
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