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Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
Genome sequencing has revealed a large number of shared and personal somatic mutations across human cancers. In principle, any genetic alteration affecting a protein-coding region has the potential to generate mutated peptides that are presented by surface HLA class I proteins that might be recogniz...
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Главные авторы: | , , , , , , , , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society of Hematology
2014
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102716/ https://ncbi.nlm.nih.gov/pubmed/24891321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567933 |
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