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Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Genome sequencing has revealed a large number of shared and personal somatic mutations across human cancers. In principle, any genetic alteration affecting a protein-coding region has the potential to generate mutated peptides that are presented by surface HLA class I proteins that might be recogniz...

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Библиографические подробности
Главные авторы: Rajasagi, Mohini, Shukla, Sachet A., Fritsch, Edward F., Keskin, Derin B., DeLuca, David, Carmona, Ellese, Zhang, Wandi, Sougnez, Carrie, Cibulskis, Kristian, Sidney, John, Stevenson, Kristen, Ritz, Jerome, Neuberg, Donna, Brusic, Vladimir, Gabriel, Stacey, Lander, Eric S., Getz, Gad, Hacohen, Nir, Wu, Catherine J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102716/
https://ncbi.nlm.nih.gov/pubmed/24891321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567933
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